RESPONSE OF CALCITONIN-GENE-RELATED PEPTIDE-LIKE IMMUNOREACTIVE NERVE-FIBERS OF THE ANTERIOR-PITUITARY TO ADRENALECTOMY IN THE RAT

被引：22

作者：

JU, G ^{[1
]}

MA, D ^{[1
]}

FAN, SC ^{[1
]}

机构：

[1] FOURTH MIL MED UNIV,DEPT MED STAT,XIAN 710032,PEOPLES R CHINA

来源：

NEUROENDOCRINOLOGY | 1994年 / 59卷 / 05期

关键词：

CALCITONIN-GENE-RELATED PEPTIDE; INNERVATION; ANTERIOR PITUITARY; ADRENALECTOMY;

D O I：

10.1159/000126697

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The mammalian anterior pituitary is known to be regulated by humoral factors only, no direct neural influence having ever been discovered. Our recent studies have shown in several species that there are substantial amounts of substance P and calcitonin-gene-related peptide-like immunoreactive (CGRP-LI) nerve fibers in the anterior pituitary and that they can make synaptic contacts with secretory cells, among which corticotropes. In the present study, we investigated changes in CGRP-LI nerve fibers of the anterior pituitary after bilateral adrenalectomy in the rat. The results show that the number of CGRP-LI nerve fibers increases significantly. In parallel, they cover a wider area of the gland after the operation, suggesting a direct neural influence.

引用

页码：505 / 510

页数：6

共 23 条

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