EFFECTS OF POLAR ADDITIVES ON THE ENZYME ENANTIOSELECTIVITY OF AN ESTERIFICATION REACTION IN ORGANIC-SOLVENTS

被引：6
|
作者：
DUAN, G
CHEN, JY
机构：
[1] Institute of Chemical Metallurgy, Academia Sinica, Beijing
来源：
BIOTECHNOLOGY LETTERS | 1994年 / 16卷 / 10期
关键词：
D O I：
10.1007/BF01022404
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The enantioselectivity of candida cylindracea lipase in esterification between ibuprofen and 1-butanol in organic solvents is influenced by adding a small amount of polar solvents. The results show that both the solvents and the amount added affected the reaction. Addition of 0.05 % ( v/v) N,N-dimethylformamide increase the ee value of the ester from 57.5 % of no addition to that of 91 %
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页码：1065 / 1068
页数：4
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