STUDIES ON THE USE OF BIDENTATE LIGANDS IN THE DIRECTED PAUSON-KHAND REACTION

被引：41

作者：

KRAFFT, ME

JULIANO, CA

机构：

[1] Department of Chemistry, Florida State University, Tallahassee

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 19期

关键词：

D O I：

10.1021/jo00045a021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of bidentate ligands in the directed Pauson-Khand reaction was investigated. Substrates with a three-carbon linkage between the two heteroatoms gave better results than substrates containing two-carbon tethers. Higher yields and better regioselectivities were observed with thioamines and bisthioethers compared to diamines. Overall, only a few bidentate substrates showed marked improvements over previous results obtained with analogous monodentate compounds. Rationalizations based on the possible modes of cycloaddition operative for the various substrates studied are presented.

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页码：5106 / 5115

页数：10

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