HIGH-DOSE METHOTREXATE FOR OSTEO-SARCOMA - TOXICITY AND CLINICAL-RESULTS

被引:22
作者
BREITHAUPT, H
KUENZLEN, E
机构
关键词
D O I
10.1159/000225700
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
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页码:85 / 89
页数:5
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共 28 条
[1]   POLYGAMMAGLUTAMYL METABOLITES OF METHOTREXATE [J].
BAUGH, CM ;
KRUMDIECK, CL ;
NAIR, MG .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 52 (01) :27-34
[2]   METHOTREXATE - CLINICAL PHARMACOLOGY, CURRENT STATUS AND THERAPEUTIC GUIDELINES [J].
BLEYER, WA .
CANCER TREATMENT REVIEWS, 1977, 4 (02) :87-101
[3]   RAPID HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC DETERMINATION OF METHOTREXATE AND ITS METABOLITES 7-HYDROXYMETHOTREXATE AND 2,4-DIAMINO-N-10-METHYLPTEROIC ACID IN BIOLOGICAL-FLUIDS [J].
BREITHAUPT, H ;
KUENZLEN, E ;
GOEBEL, G .
ANALYTICAL BIOCHEMISTRY, 1982, 121 (01) :103-113
[4]  
CARTER SK, 1978, CANCER TREAT REP, V62, P199
[5]   OSTEOGENIC SARCOMA - A STUDY OF 6 HUNDRED CASES [J].
DAHLIN, DC ;
COVENTRY, MB .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1967, A 49 (01) :101-&
[6]  
FRIEDMAN M A, 1972, Journal of Surgical Oncology, V4, P482, DOI 10.1002/jso.2930040512
[7]  
GEHAN EA, 1978, PROG CANCER RES THER, V6, P271
[8]   STOICHIOMETRIC INHIBITION OF MAMMALIAN DIHYDROFOLATE-REDUCTASE BY GAMMA-GLUTAMYL METABOLITE OF METHOTREXATE, 4-AMINO-4-DEOXY-N10-METHYLPTEROYLGLUTAMYL-GAMMA-GLUTAMATE [J].
JACOBS, SA ;
ADAMSON, RH ;
CHABNER, BA ;
DERR, CJ ;
JOHNS, DG .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 63 (03) :692-698
[9]  
JAFFE N, 1977, CANCER TREAT REP, V61, P675
[10]   ADJUVANT METHOTREXATE AND CITROVORUM-FACTOR TREATMENT OF OSTEOGENIC SARCOMA [J].
JAFFE, N ;
FREI, E ;
TRAGGIS, D ;
BISHOP, Y .
NEW ENGLAND JOURNAL OF MEDICINE, 1974, 291 (19) :994-997