The Impact of Fructose on Renal Function and Blood Pressure

被引：27

作者：

Kretowicz, Marek ^{[1
]}

Johnson, Richard J. ^{[2
]}

Ishimoto, Takuji ^{[2
]}

Nakagawa, Takahiko ^{[2
]}

Manitius, Jacek ^{[1
]}

机构：

[1] Nicolaus Copernicus Univ Toru, Coll Med Bydgoszcz, Dept Nephrol Hypertens Hypertens & Internal Med, Ul Sklodowskiej Curie 9, PL-85094 Bydgoszcz, Poland

[2] Univ Colorado Denver, Div Renal Dis & Hypertens, Denver, CO 80045 USA

来源：

INTERNATIONAL JOURNAL OF NEPHROLOGY | 2011年 / 2011卷

关键词：

D O I：

10.4061/2011/315879

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Fructose is a sugar present in sucrose, high-fructose corn syrup, honey, and fruits. Fructose intake has increased markedly in the last two centuries, primarily due to increased intake of added sugars. Increasing evidence suggests that the excessive intake of fructose may induce fatty liver, insulin resistance, dyslipidemia, hypertension, and kidney disease. These studies suggest that excessive intake of fructose might have an etiologic role in the epidemic of obesity, diabetes, and cardiorenal disease.

引用

页数：5

共 62 条

[1] Increased Fructose Consumption Is Associated with Fibrosis Severity in Patients with Nonalcoholic Fatty Liver Disease [J].

Abdelmalek, Manal F. ;

Suzuki, Ayako ;

Guy, Cynthia ;

Unalp-Arida, Aynur ;

Colvin, Ryan ;

Johnson, Richard J. ;

Diehl, Anna Mae .

HEPATOLOGY, 2010, 51 (06) :1961-1971

[2] Fructose-induced fatty liver disease - Hepatic effects of blood pressure and plasma triglyceride reduction [J].

Ackerman, Z ;

Oron-Herman, M ;

Rosenthal, MGT ;

Pappo, O ;

Link, G ;

Sela, BA .

HYPERTENSION, 2005, 45 (05) :1012-1018

[3]

Avena Nicole M, 2006, Curr Protoc Neurosci, VChapter 9, DOI 10.1002/0471142301.ns0923cs36

[4]

Bell RC, 2000, BRIT J NUTR, V84, P575

[5] DEPLETION OF LIVER ADENOSINE PHOSPHATES AND METABOLIC EFFECTS OF INTRAVENOUS INFUSION OF FRUCTOSE OR SORBITOL IN MAN AND IN RAT [J].

BODE, JC ;

ZELDER, O ;

RUMPELT, HJ ;

WITTKAMP, U .

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1973, 3 (05) :436-441

[6]

Bray GA, 2004, AM J CLIN NUTR, V79, P537

[7] Fructose ingestion acutely elevates blood pressure in healthy young humans [J].

Brown, Clive M. ;

Dulloo, Abdul G. ;

Yepuri, Gayathri ;

Montani, Jean-Pierre .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2008, 294 (03) :R730-R737

[8] DIETARY CARBOHYDRATE AND FATTY ACID SYNTHETASE ACTIVITY IN RAT LIVER AND ADIPOSE TISSUE [J].

BRUCKDORFER, KR .

BIOCHEMICAL JOURNAL, 1971, 123 (02) :P7-+

[9] Reducing Consumption of Sugar-Sweetened Beverages Is Associated With Reduced Blood Pressure A Prospective Study Among United States Adults [J].

Chen, Liwei ;

Caballero, Benjamin ;

Mitchell, Diane C. ;

Loria, Catherine ;

Lin, Pao-Hwa ;

Champagne, Catherine M. ;

Elmer, Patricia J. ;

Ard, Jamy D. ;

Batch, Bryan C. ;

Anderson, Cheryl A. M. ;

Appel, Lawrence J. .

CIRCULATION, 2010, 121 (22) :2398-2406

[10] Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells [J].

Cirillo, Pietro ;

Gersch, Michael S. ;

Mu, Wei ;

Scherer, Philip M. ;

Kim, Kyung Mee ;

Gesualdo, Loreto ;

Henderson, George N. ;

Johnson, Richard J. ;

Sautin, Yuri Y. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (03) :545-553

← 1 2 3 4 5 6 7 →