A novel and basic mechanism of immunosuppression in Chagas' disease: Trypanosoma cruzi releases in vitro and in vivo a protein which induces T cell unresponsiveness through specific interaction with cysteine and glutathione

被引：30
作者：
Ouaissi, A
GuevaraEspinoza, A
Chabe, F
GomezCorvera, R
Taibi, A
机构：
[1] Research Laboratory on Trypanosomatids, INSERM U 415, Institut Pasteur, 59019 Lille
来源：
IMMUNOLOGY LETTERS | 1995年 / 48卷 / 03期
关键词：
Trypanosoma cruzi; immunosuppression; Tc52; protein; glutathione; cysteine;
D O I：
10.1016/0165-2478(95)02463-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：221 / 224
页数：4
相关论文
共 15 条
[1]  
AZUMA M, 1993, J IMMUNOL, V150, P2091
[2]   INHIBITION OF LECTIN-INDUCED LYMPHOCYTE-ACTIVATION BY DIAMIDE AND OTHER SULFHYDRYL-REAGENTS [J].
CHAPLIN, DD ;
WEDNER, HJ .
CELLULAR IMMUNOLOGY, 1978, 36 (02) :303-311
[3]   HIV-INDUCED CYSTEINE DEFICIENCY AND T-CELL DYSFUNCTION - A RATIONALE FOR TREATMENT WITH N-ACETYLCYSTEINE [J].
DROGE, W ;
ECK, HP ;
MIHM, S .
IMMUNOLOGY TODAY, 1992, 13 (06) :211-214
[4]  
KIERSZENBAUM F, 1994, IMMUNOLOGY, V81, P462
[5]   METHOD FOR DETERMINATION OF FREE AND TOTAL GLUTATHIONE AND GAMMA-GLUTAMYLCYSTEINE CONCENTRATIONS IN HUMAN-LEUKOCYTES AND PLASMA [J].
MARTENSSON, J .
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1987, 420 (01) :152-157
[6]  
MEISTER A, 1985, METHOD ENZYMOL, V113, P571
[7]   IDENTIFICATION OF ANTI-ACETYLCHOLINESTERASE AND ANTI-IDIOTYPE ANTIBODIES IN HUMAN AND EXPERIMENTAL CHAGAS-DISEASE - PATHOLOGICAL IMPLICATIONS [J].
OUAISSI, A ;
CORNETTE, J ;
VELGE, P ;
CAPRON, A .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1988, 18 (12) :1889-1894
[8]  
OUAISSI A, 1995, IN PRESS EXP PARASIT, V81
[9]   REGULATION OF REDUCTIVE PROCESSES BY GLUTATHIONE [J].
REED, DJ .
BIOCHEMICAL PHARMACOLOGY, 1986, 35 (01) :7-13
[10]   TRYPANOSOMA-CRUZI CDNA ENCODES A TANDEMLY REPEATED DOMAIN-STRUCTURE CHARACTERISTIC OF SMALL STRESS PROTEINS AND GLUTATHIONE S-TRANSFERASES [J].
SCHONECK, R ;
PLUMASMARTY, B ;
TAIBI, A ;
BILLAUTMULOT, O ;
LOYENS, M ;
GRASMASSE, H ;
CAPRON, A ;
OUAISSI, A .
BIOLOGY OF THE CELL, 1994, 80 (01) :1-10
12