BONE-MARROW TRANSPLANT NEPHROPATHY - RADIATION NEPHRITIS REVISITED

被引：79

作者：

COHEN, EP

LAWTON, CA

MOULDER, JE

机构：

[1] MED COLL WISCONSIN,DEPT MED,MILWAUKEE,WI

[2] MED COLL WISCONSIN,DEPT RADIAT ONCOL,MILWAUKEE,WI

来源：

NEPHRON | 1995年 / 70卷 / 02期

关键词：

MARROW TRANSPLANTATION; RADIATION; HYPERTENSION; HEMOLYSIS; PLASMAPHERESIS;

D O I：

10.1159/000188587

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Late-onset renal failure occurs in up to 20% of survivors of bone marrow transplantation. Total body irradiation is a major factor in this syndrome, so-called bone marrow transplant nephropathy (BMT NP), which is defined by disproportionate anemia, hypertension, and azotemia. Previous or concurrent chemotherapy may potentiate the effect of radiation on the kidney. Kidney function may decline acutely or more gradually, with eventual long-term stabilization. Patient survival is associated with control of the blood pressure. BMT NP is a recognized complication of bone marrow transplantation, which will require ongoing attention.

引用

页码：217 / 222

页数：6

共 57 条

[1] THERAPEUTIC ADVANTAGE OF CONVERTING ENZYME-INHIBITORS IN ARRESTING PROGRESSIVE RENAL-DISEASE ASSOCIATED WITH SYSTEMIC HYPERTENSION IN THE RAT [J].