RING ENLARGEMENT OF N-HETEROCYCLES

被引:3
作者
LIANG, XT
机构
[1] Institute of Materia Medica, Beijing, 100050, Nan-wei Road
关键词
RING ENLARGEMENT; YLIDE; N-HETEROCYCLES; HALOPHILIC REAGENTS;
D O I
10.1002/jccs.199500081
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review describes our preliminary results of ring enlargement of N-heterocycles by N-ylide formation at a targeted site, exemplified by 55-->56-->58. Before development of this method, the strategy can be traced to our modified Hofmann degradation led at first to several miscarried probings on the reaction between N-halomethyl ammonium salts and halophilic reagents.
引用
收藏
页码:601 / 605
页数:5
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