ISOLATION OF ANONYMOUS, POLYMORPHIC DNA FRAGMENTS FROM HUMAN-CHROMOSOME 22Q12-QTER

被引：35
作者：
DUMANSKI, JP
VANKESSEL, AHMG
RUTTLEDGE, M
WLADIS, A
SUGAWA, N
COLLINS, VP
NORDENSKJOLD, M
机构：
[1] ERASMUS UNIV, DEPT CELL BIOL & GENET, 3000 DR ROTTERDAM, NETHERLANDS
[2] ERASMUS UNIV, DEPT CELL BIOL & GENET, 3000 DR ROTTERDAM, NETHERLANDS
[3] LUDWIG INST CANC RES, S-10401 STOCKHOLM, SWEDEN
来源：
HUMAN GENETICS | 1990年 / 84卷 / 03期
关键词：
D O I：
10.1007/BF00200562
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
A series of 195 random chromosome 22-specific probes, equivalent to approximately 1% of the size of this chromosome, have been isolated from a chromosome 22-specific bacteriophage lambda genomic library. These probes were mapped to four different regions of chromosome 22 on a panel of five somatic cell hybrids. Restriction fragment length polymorphisms were detected by 28 of the probes mapping to 22q12-qter. Evolutionarily conserved sequences in human, mouse, and Chinese hamster DNA were detected by 12% of the isolated probes. © 1990 Springer-Verlag.
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页码：219 / 222
页数：4
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