FAT DISTRIBUTION AND STEROID-HORMONES IN WOMEN WITH ALCOHOL-ABUSE

被引：26

作者：

PETTERSSON, P

ELLSINGER, BM

SJOBERG, C

BJORNTORP, P

机构：

[1] GOTHENBURG UNIV,DEPT MED 1,S-41124 GOTHENBURG,SWEDEN

[2] GOTHENBURG UNIV,NORDHEM ALCOHOL OUTPATIENT CLIN,S-41124 GOTHENBURG,SWEDEN

来源：

JOURNAL OF INTERNAL MEDICINE | 1990年 / 228卷 / 04期

关键词：

alcohol; sex steroid hormones; WHR;

D O I：

10.1111/j.1365-2796.1990.tb00238.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Abstract. Anthropometric, hormonal and liver function parameters were examined in 18 premenopausal women with a history of early alcohol abuse, and compared with the data for randomly selected controls of the same age. The alcoholic women showed slightly elevated levels of transaminases, but no clinical or laboratory signs of advanced liver damage. These women were characterized by an increased waist‐to‐hip ratio, due to enlarged waist circumference. Several endocrine abnormalities were found, including irregular or absent menses as well as low oestrogen, progesterone and Δ‐4‐androstendione levels. The concentration of free testosterone was high and that of sex‐hormone‐binding globulin was low. These data suggest abdominal distribution of body fat, as well as hyperandrogenicity in alcoholic, premenopausal women. It is postulated that the endocrine abnormalities might be responsible for the abdominal fat distribution. 1990 Blackwell Publishing Ltd

引用

收藏

页码：311 / 316

页数：6

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