GENOMICS AND PROTEOMICS METHODS AND THEIR VALUE IN BREAST CANCER DIAGNOSIS

被引：0
作者：
Atalay, Can [1 ]
机构：
[1] Ankara Onkoloji Hastanesi, Genel Cerrahi, Ankara, Turkey
来源：
JOURNAL OF BREAST HEALTH | 2010年 / 6卷 / 02期
关键词：
cancer; diagnosis; genomics; proteomics;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Genomics and proteomics are newly developing fields and becoming widely used in cancer research especially in cancer diagnosis. The aim is to review the role of genomics and proteomics to discover new breast cancer biomarkers for diagnosis with higher sensitivity and specificity. Studies reporting on potential biomarkers in breast cancer were included in this review. In the future, platforms in genomics and proteomics will be used for the discovery of tumor specific genes and related proteins, which will lead to development of novel therapeutic targets leading to patient specific therapies.
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页码：47 / 52
页数：6
相关论文
共 25 条
[1]  
Bauer KD, 2000, CLIN CANCER RES, V6, P3552
[2]   Proteomics of breast cancer - Principles and potential clinical applications [J].
Bertucci, Francois ;
Birnbaum, Daniel ;
Goncalves, Anthony .
MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (10) :1772-1786
[3]   Exploring the new world of the genome with DNA microarrays [J].
Brown, PO ;
Botstein, D .
NATURE GENETICS, 1999, 21 (Suppl 1) :33-37
[4]   Genomics and proteomics: Emerging technologies in clinical cancer research [J].
Chung, Christine H. ;
Levy, Shawn ;
Chaurand, Pierre ;
Carbone, David P. .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2007, 61 (01) :1-25
[5]   Laser capture microdissection [J].
EmmertBuck, MR ;
Bonner, RF ;
Smith, PD ;
Chuaqui, RF ;
Zhuang, ZP ;
Goldstein, SR ;
Weiss, RA ;
Liotta, LA .
SCIENCE, 1996, 274 (5289) :998-1001
[6]  
FINKE J, 1993, BIOTECHNIQUES, V14, P448
[7]   LIGHT-DIRECTED, SPATIALLY ADDRESSABLE PARALLEL CHEMICAL SYNTHESIS [J].
FODOR, SPA ;
READ, JL ;
PIRRUNG, MC ;
STRYER, L ;
LU, AT ;
SOLAS, D .
SCIENCE, 1991, 251 (4995) :767-773
[8]  
Gretzer Matthew B, 2003, Rev Urol, V5, P81
[9]  
Haab BB, 2001, GENOME BIOL, V2
[10]   SELDI-TOF-MS: the proteomics and bioinformatics approaches in the diagnosis of breast cancer [J].
Hu, Y ;
Zhang, SZ ;
Yu, JK ;
Liu, J ;
Zheng, S .
BREAST, 2005, 14 (04) :250-255
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