TIMI score as a predictor of death in patients with acute myocardial infarction without percutaneous coronary intervention

Introduction: Acute myocardial infarction (AMI) is a frequent disorder, associated with high morbidity and mortality; therefore the implementation of risk predictive models is required. Obective: To determine the value of TIMI score to predict early death risk in patients with ST-elevation AML Method: Patients with a diagnosis of ST-elevation AMI admitted in the intensive care unit (ICU) at Dr. Miguel Enriquez University Hospital were consecutively included. Death risk in ICU was assessed by using a logistic regression model, according to TIMI score at admission. Results: 115 patients were analyzed. Mean TIMI score was 5.04 (standard deviation 2.7) and the mortality rate was 10.4% Logistic regression analysis showed that the higher TIMI score was associated with increased death risk in ICU (OR 1.47 195% CI 1.17-1.83]; p=0.001); with adequate model calibration (Hosmer-Lemeshow test; X-2=5.82; p=0.324), and an area under the receiver-operating characteristic curve of 0.76 [(95% CI 0.60-0.93); p=0.003]. Conclusions: TIMI score is a good tool to predict the risk of early death in patients with ST-elevation AMI assisted in centers without percutaneous coronary intervention.