THE STRUCTURE OF BENTHOCYANIN-A - A NEW FREE-RADICAL SCAVENGER OF MICROBIAL ORIGIN

被引：39
作者：
SHINYA, K
FURIHATA, K
HAYAKAWA, Y
SETO, H
KATO, Y
CLARDY, J
机构：
[1] UNIV TOKYO,INST APPL MICROBIOL,BUNKYO KU,TOKYO 113,JAPAN
[2] CORNELL UNIV,BAKER LAB,DEPT CHEM,ITHACA,NY 14853
来源：
TETRAHEDRON LETTERS | 1991年 / 32卷 / 07期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0040-4039(00)92126-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Benthocyanin A was isolated as a potent radical scavenger from Streptomyces prunicolor. It possesses an unprecedented structure consisting of a highly conjugated furophenazine ring and a geranyl side chain as shown in Figure 1.
引用
收藏
页码：943 / 946
页数：4
相关论文
共 11 条
  • [1] PROOXIDANT STATES AND TUMOR PROMOTION
    CERUTTI, PA
    [J]. SCIENCE, 1985, 227 (4685) : 375 - 381
  • [2] BIOSYNTHESIS OF FURAQUINOCIN-A AND FURAQUINOCIN-B
    FUNAYAMA, S
    ISHIBASHI, M
    KOMIYAMA, K
    OMURA, S
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (04) : 1132 - 1133
  • [3] OXYGEN RADICALS IN THE ADULT RESPIRATORY-DISTRESS SYNDROME, IN MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY, AND IN CEREBRAL VASCULAR DAMAGE
    HAMMOND, B
    KONTOS, HA
    HESS, ML
    [J]. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1985, 63 (03) : 173 - 187
  • [4] LAVANDUCYANIN, A NEW ANTITUMOR SUBSTANCE PRODUCED BY STREPTOMYCES SP
    IMAI, S
    FURIHATA, K
    HAYAKAWA, Y
    NOGUCHI, T
    SETO, H
    [J]. JOURNAL OF ANTIBIOTICS, 1989, 42 (07) : 1196 - 1198
  • [5] BIOSYNTHETIC-STUDIES OF TERPENTECIN
    ISSHIKI, K
    TAMAMURA, T
    SAWA, T
    NAGANAWA, H
    TAKEUCHI, T
    UMEZAWA, H
    [J]. JOURNAL OF ANTIBIOTICS, 1986, 39 (11) : 1634 - 1635
  • [6] ISOLATION AND STRUCTURAL ELUCIDATION OF ANTIOXIDATIVE AGENTS, ANTIOSTATIN-A1 TO ANTIOSTATIN-A4 AND ANTIOSTATIN-B2 TO ANTIOSTATIN-B5
    MO, CJ
    SHINYA, K
    FURIHATA, K
    FURIHATA, K
    SHIMAZU, A
    HAYAKAWA, Y
    SETO, H
    [J]. JOURNAL OF ANTIBIOTICS, 1990, 43 (10) : 1337 - 1340
  • [7] ASSAY FOR LIPID PEROXIDES IN ANIMAL-TISSUES BY THIOBARBITURIC ACID REACTION
    OHKAWA, H
    OHISHI, N
    YAGI, K
    [J]. ANALYTICAL BIOCHEMISTRY, 1979, 95 (02) : 351 - 358
  • [8] ISOLATION AND STRUCTURAL ELUCIDATION OF AN ANTIOXIDATIVE AGENT, NAPHTERPIN
    SHINYA, K
    IMAI, S
    FURIHATA, K
    HAYAKAWA, Y
    KATO, Y
    VANDUYNE, GD
    CLARDY, J
    SETO, H
    [J]. JOURNAL OF ANTIBIOTICS, 1990, 43 (04) : 444 - 447
  • [9] SHINYA K, 1990, TETRAHEDRON LETT, V42, P6025
  • [10] BIOSYNTHESIS OF NAPYRADIOMYCINS
    SHIOMI, K
    IINUMA, H
    NAGANAWA, H
    ISSHIKI, K
    TAKEUCHI, T
    UMEZAWA, H
    [J]. JOURNAL OF ANTIBIOTICS, 1987, 40 (12) : 1740 - 1745
12