Congenital intrahepatic portosystemic shunts: a potential cause for early-onset neonatal cholestasis

被引：1

作者：

Narang, Radhika ^{[1
,2
]}

Patel, Minal ^{[1
]}

Tipnis, Neelesh Ajit ^{[3
]}

Tipnis, Sajani Matai ^{[1
]}

机构：

[1] Univ Mississippi, Med Ctr, Dept Pediat, 2500 N State St, Jackson, MS 39216 USA

[2] Valley Childrens Hosp, Neonatol, Pl Madera, CA USA

[3] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL USA

来源：

CASE REPORTS IN PERINATAL MEDICINE | 2018年 / 7卷 / 01期

关键词：

Bile ducts; cholestasis; congenital malformation; intrahepatic; neonate; portal vein; portosystemic shunt; vascular malformations;

D O I：

10.1515/crpm-2017-0033

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Cholestasis in the first days of life is uncommon in neonates. Neonatal cholestasis is usually associated with shock, sepsis, alloimmunity, metabolic disorders or biliary obstruction. A congenital intrahepatic portosystemic shunt results from failed involution of primordial liver vessels during the first days of life. Resulting shunts can lead to hepatic encephalopathy or liver tumors. A congenital intrahepatic portosystemic shunt should be considered when an alternative explanation cannot be found. In most cases, congenital intrahepatic portosystemic shunts will involute spontaneously by 1-2 years of age; however, surgical or radiologic closure may be needed.

引用

页数：4

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