ANALYSIS OF NONLINEARITIES IN THE FLICKER ERG

被引：79
作者：
BURNS, SA
ELSNER, AE
KREITZ, MR
机构：
[1] Eye Research Institute of Retina Foundation, Harvard Medical School, Boston, MA
来源：
OPTOMETRY AND VISION SCIENCE | 1992年 / 69卷 / 02期
关键词：
ELECTRORETINOGRAM; ERG; RETINA; NONLINEAR ANALYSIS; TEMPORAL SENSITIVITY;
D O I：
10.1097/00006324-199202000-00002
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The electroretinogram (ERG) response to steadily flickering fields shows significant nonlinear components. These nonlinear components have been used to investigate the ERG. We find the following. (1) The fundamental retinal response can be recorded at frequencies greater than 100 Hz and the second and higher harmonic responses have measurable response frequencies as high as 200 Hz. Both the fundamental response component and the second harmonic response component have multiple local maxima as a function of frequency. (2) Measurement of the response of the retina to the sum of two sine waves indicates that there is an early low-pass temporal filter in the retina. This early filter has a cutoff frequency between 40 and 50 Hz. (3) The high frequency nonlinearity is not a compressive nonlinearity.
引用
收藏
页码：95 / 105
页数：11
相关论文
共 59 条
  • [1] Baker C.L., Hess R.F., Linear and nonlinear components of human electroretinograms, J Neurophysiol, 51, pp. 952-967, (1984)
  • [2] Odom J.V., Norcia A.M., Retinal and cortical potentials: Spatial and temporal characteristics, Doc Ophthalmol Proc Ser, 40, pp. 29-38, (1984)
  • [3] Porclattl V., Non-linearities in the focal ERG evoked by pattern and uniform-field stimulation, Invest Ophthalmol Vis Sci, 28, pp. 1306-1313, (1987)
  • [4] Seiple W.H., Greenstein V., Holopigian K., Carr R.E., Changes in the focal electroretinogram with retinal eccentricity, Doc Ophthalmol, 70, pp. 29-36, (1988)
  • [5] Biersdorf W.R., Temporal factors in the foveal ERG, Curr Eye Res, 1, pp. 717-722, (1981)
  • [6] Dodt E., Wadensten L., The use of flicker electroretinography in the human eye: Observations on some normal and pathological retinae, Acta Ophthalmol (Kbh), 32, pp. 165-180, (1954)
  • [7] Fricker S.J., Application of synchronous detector techniques for electroretinographic studies in patients with retinitis pigmentosa, Invest Ophthalmol, 10, pp. 329-339, (1971)
  • [8] Marmor M.F., The electroretinogram in retinitis pigmentosa, Arch Ophthalmol, 97, pp. 1300-1304, (1979)
  • [9] Massof R.W., Johnson M.A., Sunness J.S., Perry C., Finkelstein D., Flicker electroretinogram in retinitis pigmentosa, Doc Ophthalmol, 62, pp. 231-245, (1986)
  • [10] Peckham R.H., Clinical flicker electroretinography, Am J Op-Tom Arch am Acad Optom, 45, pp. 292-308, (1968)
123456