REGIONAL ASSIGNMENT BY HYBRID MAPPING OF 36 EXPRESSED SEQUENCE TAGS (ESTS) ON HUMAN-CHROMOSOME-6

被引：20

作者：

PAPPAS, GJ

POLYMEROPOULOS, MH

BOYLE, JM

TRENT, JM

机构：

[1] UNIV MICHIGAN,DEPT HUMAN GENET,ANN ARBOR,MI 48109

[2] CHRISTIE HOSP & HOLT RADIUM INST,CANC RES CAMPAIGN,RES CTR,PATERSON INST CANC RES,MANCHESTER M20 9BX,LANCS,ENGLAND

来源：

GENOMICS | 1995年 / 25卷 / 01期

关键词：

D O I：

10.1016/0888-7543(95)80117-5

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

引用

页码：124 / 129

页数：6

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