DUAL EFFECTS OF CALCIUM ON ATP-SENSITIVE POTASSIUM CHANNELS OF FROG SKELETAL-MUSCLE

被引：14

作者：

KRIPPEITDREWS, P ^{[1
]}

LONNENDONKER, U ^{[1
]}

机构：

[1] UNIV SAARLAND,INST PHYSIOL 1,W-6650 HOMBURG,GERMANY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1108卷 / 01期

关键词：

SKELETAL MUSCLE; POTASSIUM ION CHANNEL; ATP BINDING; CALCIUM ION DEPENDENCE; (FROG);

D O I：

10.1016/0005-2736(92)90122-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The block of ATP-sensitive K+ channels by ATP were studied in inside-out patches of frog toe muscles. Seal formation within Ca2+-free Ringer induces many open channels which can be irreversibly blocked by subsequent addition of Ca2+. However, such Ca2+-blocked and ATP-blocked channels can be influenced by the addition of ATP and Ca2+: the block by ATP is partially but irreversibly cancelled.

引用

页码：119 / 122

页数：4

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