TUNNELING IN LIGAND-BINDING TO HEME PROTEINS

被引：116
|
作者：
ALBERDING, N
AUSTIN, RH
BEESON, KW
CHAN, SS
EISENSTEIN, L
FRAUENFELDER, H
NORDLUND, TM
机构：
[1] UNIV ILLINOIS, DEPT PHYS, URBANA, IL 61801 USA
[2] UNIV ILLINOIS, DEPT BIOPHYS, URBANA, IL 61801 USA
来源：
SCIENCE | 1976年 / 192卷 / 4243期
关键词：
D O I：
10.1126/science.1273579
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Rebinding of CO to the beta chain of Hb after photodissociation by a laser flash is intramolecular below about 200.degree. K. Above 25.degree. K, rebinding occurs via classical over-the-barrier motion; below, quantum-mechanical tunneling dominates. Both are described by an energy spectrum peaked at Epeak = 4.0 kjoules/mol. The barrier width d(E), determined from the energy dependence of the tunneling rate, depends on barrier height, d(E) .apprxeq. 0.05 nanometer .times. (E/Epeak)1.5.
引用
收藏
页码：1002 / 1004
页数：3
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