The effect of drugs and stimulants on gastric myoelectrical activity

被引:4
作者
Jonderko, Krzysztof [1 ]
Kwiecien, Jaroslaw [2 ]
Kasicka-Jonderko, Anna [1 ]
Buschhaus, Magdalena [3 ]
机构
[1] Sch Pharm, Dept Basic Biomed Sci, Sosnowiec, Poland
[2] Med Univ Silesia, Sch Med Zabrze, Dept Pediat, Katowice, Poland
[3] Med Res Council Technol, Ctr Therapeut Discovery, London, England
来源
PRZEGLAD GASTROENTEROLOGICZNY | 2014年 / 9卷 / 03期
关键词
drugs; drug adverse effects; electrogastrography; gastric myoelectrical activity; prokinetics;
D O I
10.5114/pg.2014.43573
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Electrogastrography (EGG) is a non-invasive diagnostic method useful for the registration and analysis of gastric myoelectrical activity. Abnormalities within an electrogastrogram were found to correlate with a number of disorders and symptoms, like functional dyspepsia, diabetic gastroparesis and terminal hepatic or renal failure. The EGG is also a valuable diagnostic method enabling the evaluation of the effect of drugs on gastric myoelectrical activity, which can be intentional, as in the case of prokinetics, or can have an adverse character. Our review focuses on drugs with a proven impact on gastric myoelectrical activity and hence on the electrogastrogram. The paper assembles and discusses the results of investigations dealing with changes in the electrogastrograms evoked by various drugs. Moreover, the mechanisms of the influence on the gastric myoelectrical activity of drugs, curative substances and stimulants are presented.
引用
收藏
页码:130 / 135
页数:6
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