Bone metabolism in children and adolescents: main characteristics of the determinants of peak bone

被引:92
作者
Stagi, Stefano [1 ]
Cavalli, Loredana [2 ]
Iurato, Chiara [1 ]
Seminara, Salvatore [1 ]
Brandi, Maria Luisa [2 ]
de Martino, Maurizio [1 ]
机构
[1] Anna Meyer Childrens Univ Hosp, Dept Hlth Sci, Viale Pieraccini 24, I-50139 Florence, Italy
[2] Univ Florence, Bone Metab Dis Unit, Dept Surg & Translat Med, Florence, Italy
关键词
bone metabolism; peak bone mass; children; vitamin D; bone growth;
D O I
10.11138/ccmbm/2013.10.3.172
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The remodelling process of bone acted by osteoblastic and osteoclastic cells allows the tissue to maintain its integrity and mechanical properties. Systemic factors, such as hormonal status, nutrition, physical inactivity, exposure to smoking, alcohol, or particular drugs, as well as a local variation in the load, can influence bone turnover, and consequently, bone mass. In this paper, physical and biochemical factors are described, which are crucially important during the period of growth, i.e. childhood and adolescence, for the construction of a healthy bone.
引用
收藏
页码:172 / 179
页数:8
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