ALCOHOLYSIS OF EPSILON-DECALACTONE WITH POLYETHYLENE GLYCOL-MODIFIED LIPASE IN 1,1,1-TRICHLOROETHANE

被引：10

作者：

FURUKAWA, M ^{[1
]}

KODERA, Y ^{[1
]}

UEMURA, T ^{[1
]}

HIROTO, M ^{[1
]}

MATSUSHIMA, A ^{[1
]}

KUNO, H ^{[1
]}

MATSUSHITA, H ^{[1
]}

INADA, Y ^{[1
]}

机构：

[1] JAPAN TOBACCO INC,LIFE SCI RES LAB,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 199卷 / 01期

关键词：

D O I：

10.1006/bbrc.1994.1190

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lipase from Pseudomonas cepacia was modified with 2,4-bis[O-methoxypoly(ethylene glycol)]-6-chloro-s-triazine, activated PEG2, to form PEG-lipase. The PEG-lipase is soluble and active in organic solvents. It catalyzes alcoholysis of racemic epsilon-decalactone with ethanol in 1,1,1 -trichloroethane to form (R)hydroxydecanoic acid ethyl ester. No alcoholysis of (S)-decalactone takes place. These results were discussed in relation to carbon number of n-alcohol, optimum temperature and comparison with modified and non-modified lipases. (C) 1994 Academic Press, Inc.

引用

页码：41 / 45

页数：5

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