HYPOMELANOSIS OF ITO AND PRECOCIOUS PUBERTY

被引：12

作者：

DAUBENEY, PEF

PAL, K

STANHOPE, R

机构：

[1] HOSP SICK CHILDREN,LONDON WC1N 3JH,ENGLAND

[2] GUYS HOSP,LONDON SE1 9RT,ENGLAND

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1993年 / 152卷 / 09期

关键词：

HYPOMELANOSIS OF ITO; PRECOCIOUS PUBERTY; GONADOTROPIN-INDEPENDENCE;

D O I：

10.1007/BF01953982

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We describe two girls with hypomelanosis of Ito, one of whom was demonstrated to have diploid-triploid mixoploidy in skin fibroblasts. Both had precocious puberty which was probably gonadotrophin-independent. The association of precocious puberty and hypomelanosis of Ito has not been previously reported. We have speculated on the possible mechanism of gonadotrophin-independent precocious puberty.

引用

收藏

页码：715 / 716

页数：2

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