CA-2+/CALMODULIN-DEPENDENT AND PROTEIN-KINASE C-DEPENDENT SIGNAL-TRANSDUCTION AFFECT SEROTONIN UPTAKE IN RAT JEJUNAL ENTEROCYTES

被引：0
作者：
TAKAYANAGI, S
HANAI, H
KANEKO, E
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来源：
BIOMEDICAL RESEARCH-TOKYO | 1993年 / 14卷
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中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
In order to determine the properties of the intestinal serotonin (5-HT) transport system, we studied 5-HT uptake by villous tip cells isolated from the rat jejunum. Isolated enterocytes were capable of 5-HT uptake. This uptake appeared to be composed of two distinct processes. At low 5-HT concentrations, most of the uptake was shown to be a result of an active transport process. In addition, we found that this system may be regulated by both Ca2+/calmodulin- and protein kinase C-dependent signal transduction.
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页码：103 / 105
页数：3
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