MEAN 24-HOUR GROWTH-HORMONE AND TESTOSTERONE CONCENTRATIONS IN RELATION TO PUBERTAL GROWTH SPURT IN BOYS WITH NORMAL OR DELAYED PUBERTY

被引：30

作者：

BUTENANDT, O ^{[1
]}

EDER, R ^{[1
]}

WOHLFARTH, K ^{[1
]}

BIDLINGMAIER, F ^{[1
]}

KNORR, D ^{[1
]}

机构：

[1] UNIV MUNCHEN DR VON HAUNERSCHEN KINDER SPITAL, KINDER KLIN, PADIAT ENDOKRINOL ABT, D-8000 Munich 2, GERMANY

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1976年 / 122卷 / 02期

关键词：

D O I：

10.1007/BF00466266

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The mean growth hormone concentration during a 24 h period in 7 boys of short familial stature and a growth rate of 3.2-5.4 cm/yr was between 1.0-4.6 ng/ml serum. In 7 boys with pubertal growth spurt and familial tallness (growth rate 7.2-11.0 cm/yr) it varied from 0.97-4.4 ng/ml, and in 6 boys with constitutional delay of puberty (a growth rate of 4.2-5.2 cm/yr prior to puberty) from 1.3-4.3 ng/ml. No correlation was found between the 24 h mean growth hormone concentration and the mean 24 h testosterone concentration in serum or the growth rate, but a correlation was found between testosterone and the growth rate. The growth spurt in puberty is not due to a change in growth hormone concentration but rather to the increase of androgen production in puberty.

引用

页码：85 / 92

页数：8

共 22 条

[1] TEMPORAL PATTERNS OF INTEGRATED PLASMA HORMONE LEVELS DURING SLEEP AND WAKEFULNESS .1. THYROID-STIMULATING HORMONE, GROWTH-HORMONE AND CORTISOL [J].