MATING PATTERNS IN MALARIA PARASITE POPULATIONS OF PAPUA-NEW-GUINEA

被引：268
作者：
PAUL, REL
PACKER, MJ
WALMSLEY, M
LAGOG, M
RANFORDCARTWRIGHT, LC
PARU, R
DAY, KP
机构：
[1] UNIV OXFORD, DEPT ZOOL, WELLCOME CTR EPIDEMIOL INFECT DIS, OXFORD OX1 3PS, ENGLAND
[2] PAPUA NEW GUINEA INST MED RES, MADANG, PAPUA N GUINEA
[3] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED, DEPT BIOL, LONDON SW7 2BB, ENGLAND
[4] UNIV EDINBURGH, INST CELL ANIM & POPULAT BIOL, DIV BIOL SCI, EDINBURGH EH9 3JT, MIDLOTHIAN, SCOTLAND
来源：
SCIENCE | 1995年 / 269卷 / 5231期
基金：
英国惠康基金;
关键词：
D O I：
10.1126/science.7569897
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Description of the genetic structure of malaria parasite populations is central to an understanding of the spread of multiple-locus drug and vaccine resistance. The Plasmodium falciparum mating patterns from Madang, Papua New Guinea, where intense transmission of malaria occurs, are described here. A high degree of inbreeding occurs in the absence of detectable linkage disequilibrium. This contrasts with other studies, indicating that the genetic structure of malaria parasite populations is neither clonal nor panmictic but will vary according to the transmission characteristics of the region.
引用
收藏
页码：1709 / 1711
页数：3
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