THE STRUCTURE OF THE QUINOPROTEIN ALCOHOL-DEHYDROGENASE OF ACETOBACTER-ACETI MODELED ON THAT OF METHANOL DEHYDROGENASE FROM METHYLOBACTERIUM-EXTORQUENS

被引：32
作者：
COZIER, GE [1 ]
LAN, IG [1 ]
ANTHONY, C [1 ]
机构：
[1] UNIV SOUTHAMPTON, SERC, CTR MOLEC RECOGNIT, DEPT BIOCHEM, SOUTHAMPTON SO16 7PX, HANTS, ENGLAND
来源：
BIOCHEMICAL JOURNAL | 1995年 / 308卷
基金：
英国惠康基金;
关键词：
D O I：
10.1042/bj3080375
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The 1.94 Angstrom structure of methanol dehydrogenase has been used to provide a model structure for part of a membrane quinohaemoprotein alcohol dehydrogenase. The basic superbarrel structure and the active-site region are retained, indicating essentially similar mechanisms of action, but there are considerable differences in the external loops, particularly those involved in formation of the shallow funnel leading to the active site.
引用
收藏
页码：375 / 379
页数：5
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