A DIRECT REPEAT IS A HOTSPOT FOR LARGE-SCALE DELETION OF HUMAN MITOCHONDRIAL-DNA

被引：516
|
作者：
SCHON, EA [1 ]
RIZZUTO, R [1 ]
MORAES, CT [1 ]
NAKASE, H [1 ]
ZEVIANI, M [1 ]
DIMAURO, S [1 ]
机构：
[1] COLUMBIA UNIV, DEPT GENET & DEV, NEW YORK, NY 10027 USA
来源：
SCIENCE | 1989年 / 244卷 / 4902期
关键词：
D O I：
10.1126/science.2711184
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：346 / 349
页数：4
相关论文
共 50 条
  • [21] The generation of mitochondrial DNA large-scale deletions in human cells
    Tao Chen
    Jing He
    Yushan Huang
    Weiwei Zhao
    Journal of Human Genetics, 2011, 56 : 689 - 694
  • [22] CYTOPLASMIC BODY AND MITOCHONDRIAL-DNA DELETION
    SAHASHI, K
    OHNO, K
    TANAKA, M
    IBI, T
    YAMAMOTO, T
    TASHIRO, M
    SATO, W
    TAKAHASHI, A
    OZAWA, T
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 1990, 99 (2-3) : 291 - 300
  • [23] A GC CLUSTER REPEAT IS A HOTSPOT FOR MIT- MACRO-DELETIONS IN YEAST MITOCHONDRIAL-DNA
    WEILLER, GF
    BRUCKNER, H
    KIM, SH
    PRATJE, E
    SCHWEYEN, RJ
    MOLECULAR & GENERAL GENETICS, 1991, 226 (1-2): : 233 - 240
  • [24] DELETION OF BLOOD MITOCHONDRIAL-DNA IN PANCYTOPENIA
    ROTIG, A
    COLONNA, M
    BLANCHE, S
    FISCHER, A
    LEDEIST, F
    FREZAL, J
    SAUDUBRAY, JM
    MUNNICH, A
    LANCET, 1988, 2 (8610): : 567 - 568
  • [25] MITOCHONDRIAL-DNA DELETION IN OCULOSKELETAL MYOPATHY
    MERELLI, E
    SELLERI, L
    FERRARI, S
    SOLA, P
    COLOMBO, A
    TORELLI, G
    EUROPEAN NEUROLOGY, 1991, 31 (03) : 160 - 163
  • [26] Effect of oxidative stress on mitochondria in human cells bearing elevated levels of a large-scale deletion in mitochondrial DNA
    Siegenthaler, Matthew
    Pogozelski, Wendy
    FASEB JOURNAL, 2011, 25
  • [27] Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes
    Jacoby, Elad
    Bar-Yosef, Omer
    Gruber, Noah
    Lahav, Einat
    Varda-Bloom, Nira
    Bolkier, Yoav
    Bar, Diana
    Blumkin, Moriya Ben-Yakir
    Barak, Sharon
    Eisenstein, Etzyona
    Ahonniska-Assa, Jaana
    Silberg, Tamar
    Krasovsky, Tal
    Bar, Orly
    Erez, Neta
    Bielorai, Bella
    Golan, Hana
    Dekel, Benjamin
    Besser, Michal J.
    Pozner, Gat
    Khoury, Hanan
    Jacobs, Alan
    Campbell, John
    Herskovitz, Eli
    Sher, Noa
    Yivgi-Ohana, Natalie
    Anikster, Yair
    Toren, Amos
    SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (676)
  • [28] Single large-scale mitochondrial DNA deletion in a patient with mitochondrial myopathy associated with multiple symmetric lipomatosis
    Campos, Y
    Martin, MA
    Navarro, C
    Gordo, P
    Arenas, J
    NEUROLOGY, 1996, 47 (04) : 1012 - 1014
  • [29] Endocrine Abnormalities and Growth Pattern in Single Large-Scale Mitochondrial DNA Deletion Syndromes
    Daka, Ayman
    Lahav, Einat
    Bar-Yosef, Omer
    Bolkier, Yoav
    Levy-Shraga, Yael
    Anikster, Yair
    Jacoby, Elad
    Gruber, Noah
    HORMONE RESEARCH IN PAEDIATRICS, 2024, 97 : 425 - 425
  • [30] Endocrine Abnormalities and Growth Pattern in Single Large-Scale Mitochondrial DNA Deletion Syndromes
    Daka, Ayman
    Lahav, Einat
    Yosef, Omer Bar
    Bolkier, Yoav
    Levy-Shraga, Yael
    Anikster, Yair
    Jacoby, Elad
    Gruber, Noah
    ACTA PAEDIATRICA, 2025,
12345