DOSE-VOLUME EFFECTS IN THE SPINAL-CORD

被引：60

作者：

VANDERKOGEL, AJ

机构：

[1] Institute of Radiotherapy, University of Nijmegen, 6500 HB Nijmegen, Geert Grooteplein 32

来源：

RADIOTHERAPY AND ONCOLOGY | 1993年 / 29卷 / 02期

关键词：

CNS TOLERANCE; RADIATION MYELOPATHY; DOSE-VOLUME RELATIONSHIPS; MATHEMATICAL MODELS;

D O I：

10.1016/0167-8140(93)90234-Y

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Experimental data on dose-volume relationships for the spinal cord are now available for a variety of animal models (monkey, dog, pig, rat) Most studies show a marginal volume effect for cord lengths longer than 1 cm, but a steep increase in tolerance doses for irradiated lengths of less than 1 cm. From a comparison of several theoretical models with available clinical/experimental data it can be concluded that there is at present no need for a further expansion of models, but a great need of reliable data.

引用

页码：105 / 109

页数：5

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