Osmotic demyelination syndrome following slow correction of hyponatremia: Possible role of hypokalemia

被引：20

作者：

Koul, Parvaiz A. ^{[1
]}

Khan, Umar Hafiz ^{[1
]}

Jan, Rafi A. ^{[1
]}

Shah, Sanaullah ^{[1
]}

Qadri, Abdul Baseer ^{[1
]}

Wani, Burhan ^{[1
]}

Ashraf, Mohammed ^{[1
]}

Ahmad, Feroze ^{[1
]}

Bazaz, Sajjad R. ^{[1
]}

机构：

[1] Sheri Kashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar 190011, Jammu & Kashmir, India

来源：

INDIAN JOURNAL OF CRITICAL CARE MEDICINE | 2013年 / 17卷 / 04期

关键词：

Electrolyte disturbances; hypokalemia; hyponatremia; locked-in state;

D O I：

10.4103/0972-5229.118433

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 47-year-old male presented with hyponatremia that was corrected slowly as per the recommended guidelines. The patient improved initially but went on to develop a quadriparesis with a locked-in state due to a central as well as extrapontine myelinolysis and subsequently succumbed to an intercurrent infective illness. The patient had associated hypokalemia. Hyponatremia can result in central pontine myelinolysis even when the electrolyte disorder is treated slowly, and the concomitant hypokalemia seems to play a contributory role in the pathogenesis of the neurological disorder.

引用

页码：231 / 233

页数：3

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