THE ROLE OF THE HYDROGEN-BOND AND WATER IN BIOLOGICAL PROCESSES

被引：24
|
作者：
JEFFREY, GA
机构：
[1] Department of Crystallography, University of Pittsburgh, Pittsburgh
来源：
JOURNAL OF MOLECULAR STRUCTURE | 1994年 / 322卷
关键词：
D O I：
10.1016/0022-2860(94)87017-9
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Water plays a role in biological systems both as a packing molecule and as an attenuator of strong hydrogen bonds which might otherwise restrict conformational flexibility. It is suggested that the non-additivity or cooperative property of chains of hydroxy bonds can provide a steering component to add to the ''lock and key'' analogy of substrate-receptor interactions.
引用
收藏
页码：21 / 25
页数：5
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