A COMPARISON BETWEEN MUSCARINIC RECEPTOR OCCUPANCY, ADENYLATE-CYCLASE INHIBITION, AND INOTROPIC RESPONSE IN HUMAN-HEART

被引:41
作者
DELHAYE, M
DESMET, JM
TATON, G
DENEEF, P
CAMUS, JC
FONTAINE, J
WAELBROECK, M
ROBBERECHT, P
CHRISTOPHE, J
机构
[1] UNIV LIBRE BRUXELLES,B-1000 BRUSSELS,BELGIUM
[2] ACAD HOSP ERASME,DEPT GASTROENTEROL,BRUSSELS,BELGIUM
[3] ACAD HOSP ERASME,DEPT CARDIAC SURG,BRUSSELS,BELGIUM
[4] UNIV LIBRE BRUXELLES,SCH MED,DEPT PHARMACOL,B-1000 BRUSSELS,BELGIUM
关键词
D O I
10.1007/BF00506197
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:170 / 175
页数:6
相关论文
共 31 条
[1]  
ARIENS EJ, 1960, ARCH INT PHARMACOD T, V127, P459
[2]   GUANINE-NUCLEOTIDES MODULATE MUSCARINIC RECEPTOR-BINDING IN THE HEART [J].
BERRIE, CP ;
BIRDSALL, NJM ;
BURGEN, ASV ;
HULME, EC .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1979, 87 (04) :1000-1005
[3]   DUAL MECHANISM FOR INHIBITION OF CALCIUM-DEPENDENT ACTION-POTENTIALS BY ACETYLCHOLINE IN AVIAN VENTRICULAR MUSCLE - RELATIONSHIP TO CYCLIC-AMP [J].
BIEGON, RL ;
PAPPANO, AJ .
CIRCULATION RESEARCH, 1980, 46 (03) :353-362
[4]  
BROWN JH, 1979, J CYCLIC NUCL PROT, V5, P423
[5]   MUSCARINIC RECEPTOR OF HEART CELL-MEMBRANES - ASSOCIATION WITH AGONISTS, ANTAGONISTS AND ANTIARRHYTHMIC AGENTS [J].
CAVEY, D ;
VINCENT, JP ;
LAZDUNSKI, M .
FEBS LETTERS, 1977, 84 (01) :110-114
[6]  
CHENG Y, 1973, BIOCHEM PHARMACOL, V22, P3099
[7]  
EHLERT FJ, 1981, FED PROC, V40, P153
[8]  
FIELDS JZ, 1978, J BIOL CHEM, V253, P3251
[9]  
GARDNER JD, 1979, GASTROENTEROLOGY, V76, P202
[10]   GTP-DEPENDENT INHIBITION OF CARDIAC ADENYLATE-CYCLASE BY MUSCARINIC CHOLINERGIC AGONISTS [J].
JAKOBS, KH ;
AKTORIES, K ;
SCHULTZ, G .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 310 (02) :113-119