Latest evidence on using hormone replacement therapy in the menopause

Key content Hormone replacement therapy (HRT) is the most effective treatment for symptoms of estrogen deficiency. When HRT is individually tailored women gain maximum advantages and the risks are minimised. Several types and regimens of HRT and different routes of delivery exist. Results from studies using only one type and route may not therefore apply to all users. The use of HRT is an individual decision, which a woman can only make once she has been given correct information and advice from healthcare professionals. HRT should be recommended in women with premature ovarian insufficiency with advice to continue until the average age of the menopause at 51.4 years. Learning objectives To review the current research and the evidence on the use of HRT in women. Application of the evidence in relation to the management of the symptomatic menopausal woman. To promote confidence in prescribing HRT in most symptomatic women. To have a general overview of prescribing in women with relative contraindications. Ethical issues The use of HRT is a patient informed choice. Where evidence is limited and quality of life a priority, then a multidisciplinary approach may be necessary and informed written consent documented.