Analgesic and Anti Microbial Activity of Aerial Parts of Polygonum Glabraum

The Methanol and Petroleum ether extract of the aerial parts of polygonum glabraum was investigated for its analgesic activity in animal models. The methanol and pet ether extract at 200 mg/kg body weight in the acetic acid induced writhing model, the extract showed a good analgesic effect characterized by reduction in the number of writhes when compared to control. The both extract were screened for their antibacterial activity by filter paper disc method. The extracts were tested against Staphylocccusaureus and Pseudomonas aureginosaand fungi like Candida albicans. The susceptibility of the microorganisms to the extracts of the leaves of plant was compared with selected standard antibiotics (Amikacin 5 mu gm/ml) and Ketoconazole (10 mu gm/ml). The methanol extract the zone of inhibition is 15 mm in S. aureus and 12 mm in P. auregenosa for anti bacterial activity. The antifungal activity against candida albicans in methanolic extract is 11mm.