SIGNAL TRANSDUCTION IN YEAST MATING - RECEPTORS, TRANSCRIPTION FACTORS, AND THE KINASE CONNECTION

被引：68
作者：
SPRAGUE, GF [1 ]
机构：
[1] UNIV OREGON,DEPT BIOL,EUGENE,OR 97403
来源：
TRENDS IN GENETICS | 1991年 / 7卷 / 11-12期
关键词：
D O I：
10.1016/0168-9525(91)90262-O
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. Binding of pheromone to G-protein-coupled receptors activates a cascade of serine/threonine protein kinases that ultimately phosphorylate and increase the activity of an identified transcription factor.
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页码：393 / 398
页数：6
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