SYNTHESIS AND ADRENORECEPTOR BLOCKING ACTION OF AZIRIDINIUM IONS DERIVED FROM PHENOXYBENZAMINE AND DIBENAMINE

被引：25
作者：
HENKEL, JG
PORTOGHESE, PS
MILLER, JW
LEWIS, P
机构：
[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455
[2] UNIV MINNESOTA,DEPT PHARMACOL,MINNEAPOLIS,MN 55455
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1976年 / 19卷 / 01期
关键词：
D O I：
10.1021/jm00223a002
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：6 / 10
页数：5
相关论文
共 17 条
[1]   DI-N-SUBSTITUTED 2-HALOGENOETHYLAMINES .3. N-2(OR 3 OR 4)-CHLOROBENZYL-N-ETHYL DERIVATIVES - SYNTHESIS, REACTIVITY, AND PHARMACOLOGY [J].
ALLEN, JF ;
CHAPMAN, NB .
JOURNAL OF THE CHEMICAL SOCIETY, 1960, (APR) :1482-1487
[2]   DI-N-SUBSTITUTED 2-HALOGENOETHYLAMINES .4. NN-BIS-2'-ARYLOXYETHYL DERIVATIVES - SYNTHESES, REACTIVITY, AND PHARMACOLOGY [J].
ALLEN, JF ;
CHAPMAN, NB .
JOURNAL OF THE CHEMICAL SOCIETY, 1961, (MAR) :1076-&
[3]  
CHAPMAN NB, 1954, J CHEM SOC, P2103
[4]  
CHAPMAN NB, 1967, DRUGS AFFECTING PERI, V1
[5]  
Frost AA, 1961, KINETICS MECHANISM, P166
[6]  
GOLDSTEIN A, 1964, BIOSTATISTICS INTRO, pCH4
[7]   ETHYLENEIMINIUM ION AS THE ACTIVE SPECIES IN 2-HALOALKYLAMINE COMPOUNDS [J].
GRAHAM, JDP .
BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1957, 12 (04) :489-497
[8]  
GRAHAM JDP, 1962, PROGR MEDICINAL CHEM, V2, P158
[9]  
HARVEY SC, 1953, J PHARMACOL EXP THER, V109, P328
[10]  
HENKEL JG, 1972, THESIS BROWN U
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