WY-48,090 - A NOVEL LEUKOTRIENE-D4 ANTAGONIST WITH ADDITIONAL ANTIINFLAMMATORY ACTIVITY

被引：0
|
作者：
KREFT, AF
MUSSER, JH
CARLSON, RP
CHANG, JY
HAND, JM
机构：
[1] WYETH LABS INC,MED CHEM SECT,PHILADELPHIA,PA 19101
[2] WYETH LABS INC,EXPTL THERAPEUT SECT,PHILADELPHIA,PA 19101
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1987年 / 194卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：62 / MEDI
相关论文
共 50 条
  • [31] BRONCHODILATOR PROPERTIES OF AN INHALED LEUKOTRIENE-D4 ANTAGONIST (VERLUKAST-MK-0679) IN ASTHMATIC-PATIENTS
    LAMMERS, JWJ
    VANDAELE, P
    VANDENELSHOUT, FMJ
    DECRAMER, M
    BUNTINX, A
    DELEPELEIRE, I
    FRIEDMAN, B
    PULMONARY PHARMACOLOGY, 1992, 5 (02): : 121 - 125
  • [32] PHARMACOLOGICAL STUDY OF THE CONTRACTILE ACTIVITY OF LEUKOTRIENE-C4 AND LEUKOTRIENE-D4 ON ISOLATED HUMAN AIRWAY SMOOTH-MUSCLE
    DAVIS, C
    JONES, TR
    DANIEL, EE
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1982, 125 (04): : 65 - 65
  • [33] PHARMACOLOGICAL STUDY OF THE CONTRACTILE ACTIVITY OF LEUKOTRIENE-C4 AND LEUKOTRIENE-D4 ON ISOLATED HUMAN AIRWAY SMOOTH-MUSCLE
    JONES, TR
    DAVIS, C
    DANIEL, EE
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1982, 60 (05) : 638 - 643
  • [34] THE EFFECT OF THE ORAL LEUKOTRIENE ANTAGONIST, ICI 204,219, ON LEUKOTRIENE-D4 AND HISTAMINE-INDUCED CUTANEOUS VASCULAR REACTIONS IN MAN
    BERNSTEIN, JA
    GREENBERGER, PA
    PATTERSON, R
    GLASS, M
    KRELL, R
    THYRUM, PT
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1991, 87 (01) : 93 - 98
  • [35] BRONCHODILATION WITH A POTENT AND SELECTIVE LEUKOTRIENE-D4 (LTD4) RECEPTOR ANTAGONIST (MK-571) IN PATIENTS WITH ASTHMA
    GADDY, JN
    MARGOLSKEE, DJ
    BUSH, RK
    WILLIAMS, VC
    BUSSE, WW
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1992, 146 (02): : 358 - 363
  • [36] LEUKOTRIENE-D4 (LTD4) ANTAGONIST ICI-204, 219 RELIEVES RAGWEED ALLERGIC RHINITIS SYMPTOMS
    DONNELLY, A
    GLASS, M
    MULLER, B
    SMART, S
    HUTSON, J
    MINKWITZ, MC
    CASALE, TB
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1993, 91 (01) : 259 - 259
  • [37] INFLUENCE OF LEUKOTRIENE-D4 ON ARTERIAL-PRESSURE AND GASTROINTESTINAL ELECTRICAL-ACTIVITY IN THE CONSCIOUS PIGLET
    WECHSUNG, E
    DESAEDELEER, V
    HOUVENAGHEL, A
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 1992, 46 (01): : 27 - 31
  • [38] PROTECTIVE EFFECTS OF A THROMBOXANE SYNTHETASE INHIBITOR, A THROMBOXANE ANTAGONIST, A LIPOXYGENASE INHIBITOR AND A LEUKOTRIENE-C4, LEUKOTRIENE-D4 ANTAGONIST ON MYOCARDIAL INJURY CAUSED BY ACUTE MYOCARDIAL-INFARCTION IN THE CANINE HEART
    ITO, T
    TOKI, Y
    HIEDA, N
    OKUMURA, K
    HASHIMOTO, H
    OGAWA, K
    SATAKE, T
    JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 1989, 53 (09): : 1115 - 1121
  • [39] SPECIES-DEPENDENT ENANTIOSELECTIVE PLASMA-PROTEIN BINDING OF MK-571, A POTENT LEUKOTRIENE-D4 ANTAGONIST
    LIN, JH
    DELUNA, FA
    ULM, EH
    TOCCO, DJ
    DRUG METABOLISM AND DISPOSITION, 1990, 18 (04) : 484 - 487
  • [40] DEVELOPMENT OF A NOVEL SERIES OF (2-QUINOLINYLMETHOXY)PHENYL-CONTAINING COMPOUNDS AS HIGH-AFFINITY LEUKOTRIENE-D4 RECEPTOR ANTAGONISTS .4. ADDITION OF CHROMONE MOIETY ENHANCES LEUKOTRIENE-D4 RECEPTOR-BINDING AFFINITY
    HUANG, FC
    GALEMMO, RA
    POLI, GB
    LEARN, KS
    MORRISSETTE, MM
    JOHNSON, WH
    DANKULICH, WP
    CAMPBELL, HF
    CARNATHAN, GW
    VANINWEGEN, RG
    JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (05) : 1704 - 1707
12345