PRIMARY STRUCTURES AND PROPERTIES OF 2 RELATED FORMS OF ARYL SULFOTRANSFERASES IN HUMAN LIVER

被引：49

作者：

OZAWA, S ^{[1
]}

NAGATA, K ^{[1
]}

SHIMADA, M ^{[1
]}

UEDA, M ^{[1
]}

TSUZUKI, T ^{[1
]}

YAMAZOE, Y ^{[1
]}

KATO, R ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT SURG,SHINJUKU KU,TOKYO 160,JAPAN

来源：

PHARMACOGENETICS | 1995年 / 5卷

关键词：

D O I：

10.1097/00008571-199512001-00015

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

cDNAs and genes of ST1A2 and ST1A3 were isolated from human liver cDNA and genomic libraries and shown to encode arylsulfotransferases. Studies on their mRNAs and proteins expressed indicate the existence of two distinct phenol-sulfating enzymes which are involved in the metabolic activation of carcinogenic arylamines in human livers.

引用

页码：S135 / S140

页数：6

共 17 条

[1] SULFOTRANSFERASE-MEDIATED DNA-BINDING OF N-HYDROXYARYLAMINES(AMIDE) IN LIVER CYTOSOLS FROM HUMAN AND EXPERIMENTAL-ANIMALS
ABUZEID, M
YAMAZOE, Y
KATO, R
[J]. CARCINOGENESIS, 1992, 13 (08) : 1307 - 1314
[2] HUMAN-LIVER PHENOL SULFOTRANSFERASE - ASSAY CONDITIONS, BIOCHEMICAL-PROPERTIES AND PARTIAL-PURIFICATION OF ISOZYMES OF THE THERMOSTABLE FORM
CAMPBELL, NRC
VANLOON, JA
WEINSHILBOUM, RM
[J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (09) : 1435 - 1446
[3] MOLECULAR ENZYMOLOGY OF HUMAN LIVER CYTOSOLIC SULFOTRANSFERASES
FALANY, CN
[J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (07) : 255 - 259
[4] SULFATION OF MINOXIDIL BY HUMAN LIVER PHENOL SULFOTRANSFERASE
FALANY, CN
KERL, EA
[J]. BIOCHEMICAL PHARMACOLOGY, 1990, 40 (05) : 1027 - 1032
[5] PURIFICATION OF HEPATIC N-HYDROXYARYLAMINE SULFOTRANSFERASES AND THEIR REGULATION BY GROWTH-HORMONE AND THYROID-HORMONE IN RATS
GONG, DW
OZAWA, S
YAMAZOE, Y
KATO, R
[J]. JOURNAL OF BIOCHEMISTRY, 1991, 110 (02) : 226 - 231
[6] HEROUX JA, 1988, MOL PHARMACOL, V34, P194
[7] JAKOBY WB, 1980, ENZYMATIC BASIS DETO, P199
[8] GENERATION OF REACTIVE METABOLITES OF NORMAL-HYDROXY-PHENACETIN BY GLUCURONIDATION AND SULFATION
MULDER, GJ
HINSON, JA
GILLETTE, JR
[J]. BIOCHEMICAL PHARMACOLOGY, 1977, 26 (03) : 189 - 196
[9] PHENOL SULFOTRANSFERASE AND URIDINE-DIPHOSPHATE GLUCURONYLTRANSFERASE FROM RAT-LIVER INVIVO AND INVITRO - 2,6-DICHLORO-4-NITROPHENOL AS SELECTIVE INHIBITOR OF SULFATION
MULDER, GJ
SCHOLTENS, E
[J]. BIOCHEMICAL JOURNAL, 1977, 165 (03) : 553 - 559
[10] NAGATA K, 1993, J BIOL CHEM, V268, P24720

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