PRIMARY STRUCTURES AND PROPERTIES OF 2 RELATED FORMS OF ARYL SULFOTRANSFERASES IN HUMAN LIVER

被引：49

作者：

OZAWA, S ^{[1
]}

NAGATA, K ^{[1
]}

SHIMADA, M ^{[1
]}

UEDA, M ^{[1
]}

TSUZUKI, T ^{[1
]}

YAMAZOE, Y ^{[1
]}

KATO, R ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT SURG,SHINJUKU KU,TOKYO 160,JAPAN

来源：

PHARMACOGENETICS | 1995年 / 5卷

关键词：

D O I：

10.1097/00008571-199512001-00015

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

cDNAs and genes of ST1A2 and ST1A3 were isolated from human liver cDNA and genomic libraries and shown to encode arylsulfotransferases. Studies on their mRNAs and proteins expressed indicate the existence of two distinct phenol-sulfating enzymes which are involved in the metabolic activation of carcinogenic arylamines in human livers.

引用

页码：S135 / S140

页数：6

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