LATE-ONSET DYSTHYROID OPTIC NEUROPATHY

被引:10
作者
CHOU, PI
FELDON, SE
机构
[1] DOHENY EYE INST,LOS ANGELES,CA 90033
[2] UNIV SO CALIF,SCH MED,DEPT NEUROL SURG,LOS ANGELES,CA 90033
[3] UNIV SO CALIF,SCH MED,DEPT OPHTHALMOL,LOS ANGELES,CA 90033
关键词
D O I
10.1089/thy.1994.4.213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report three rare occurrences of late onset dysthyroid optic neuropathy. We reviewed each case in detail and found that these middle-aged patients developed onset of optic neuropathy 7 to 12 years following stabilization of clinically significant, stable ophthalmopathy. There was no corresponding reactivation of orbital inflammatory symptoms or signs. Characteristic of a Graves' ophthalmopathy, the vision was responsive to either corticosteroid or surgical decompression, or to a combination thereof. None of the patients had diabetes, hypertensive, or cardiovascular disease. We hypothesize that in these unique cases possible mechanical vascular factors may have induced decompensation of optic nerve function in otherwise stable disease.
引用
收藏
页码:213 / 216
页数:4
相关论文
共 13 条
[1]  
DAY RM, 1962, ARCH OPHTHALMOL-CHIC, V67, P289
[2]  
FELDON SE, 1984, ARCH OPHTHALMOL-CHIC, V102, P1469, DOI 10.1001/archopht.1984.01040031189015
[3]  
FRUEH BR, 1983, ORBIT, V2, P199
[4]  
HALES IB, 1960, Q J MED, V29, P113
[5]   GRAVES OPHTHALMOPATHY - ROLE OF MR IMAGING IN RADIATION-THERAPY [J].
JUST, M ;
KAHALY, G ;
HIGER, HP ;
ROSLER, HP ;
KUTZNER, J ;
BEYER, J ;
THELEN, M .
RADIOLOGY, 1991, 179 (01) :187-190
[6]  
KENNERDELL JS, 1981, ARCH OPHTHALMOL-CHIC, V99, P807
[7]  
PRUMMEL MF, 1993, OPHTHALMOLOGY, V100, P556
[8]  
Rootman J, 1988, DIS ORBIT, P241
[9]   ABILITY OF MONOCLONAL-ANTIBODIES TO THE THYROTROPIN RECEPTOR TO INCREASE COLLAGEN-SYNTHESIS IN HUMAN-FIBROBLASTS - AN ASSAY WHICH APPEARS TO MEASURE EXOPHTHALMOGENIC IMMUNOGLOBULINS IN GRAVES SERA [J].
ROTELLA, CM ;
ZONEFRATI, R ;
TOCCAFONDI, R ;
VALENTE, WA ;
KOHN, LD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 62 (02) :357-367
[10]  
RUNDLE FF, 1945, LANCET, V1, P51