NEURONAL PROTEIN GAP-43 IS A MEMBER OF NOVEL GROUP OF BRAIN ACID-SOLUBLE PROTEINS (BASPS)

被引:23
|
作者
MOSEVITSKY, MI
NOVITSKAYA, VA
PLEKHANOV, AY
SKLADCHIKOVA, GY
机构
[1] Division of Molecular and Radiation Biophysics, Petersburg Nuclear Physics Institute, Gatchina, Leningrad District Leningrad,
关键词
BRAIN-SPECIFIC PROTEINS; BRAIN ACID-SOLUBLE PROTEINS; GAP-43; B-50; HMG;
D O I
10.1016/0168-0102(94)90146-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A group of brain acid-soluble proteins (BASPs) is preliminarily characterized. In some respects BASPs are similar to high mobility group (HMG) proteins, but in contrast to HMG, all BASPs are very acidic (pI 4.4-4.6) and show abnormal mobility during SDS-PAGE electrophoresis. BASP2-1 and BASP2-2 are identified as the two forms of neuronal protein GAP-43 (B-50, pp46, F1, neuromodulin). BASP1 and BASP3 are apparently novel brain proteins.
引用
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页码:223 / 228
页数:6
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