LIPID-LADEN FOAMY MACROPHAGES IN RENAL-CELL CARCINOMA - POTENTIAL FROZEN-SECTION DIAGNOSTIC PITFALL

被引：6

作者：

ISKANDAR, SS

PRAHLOW, JA

WHITE, WL

机构：

[1] Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem

来源：

PATHOLOGY RESEARCH AND PRACTICE | 1993年 / 189卷 / 05期

关键词：

FOAMY MACROPHAGES; RENAL CELL CARCINOMA; XANTHOGRANULOMATOUS PYELONEPHRITIS;

D O I：

10.1016/S0344-0338(11)80364-X

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Lipid-laden foamy macrophages are characteristic of xanthogranulomatous pyelonephritis (XGP). We have encountered a case of renal cell carcinoma (RCC), with extensive necrosis, in which confluent sheets of foamy macrophages were a dominant feature. We describe the case and discuss the potential frozen section diagnostic problem in attempting to distinguish between confluent sheets of xanthoma cells as a ''reactive'' change in RCC and xanthoma cells as a fundamental component of XGP. We propose that awareness of that problem should prompt the pathologist to request additional samples.

引用

页码：549 / 552

页数：4

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