ISONIAZID, TRICYCLICS AND THE CHEESE REACTION

被引：9

作者：

DIMARTINI, A

机构：

[1] Western Psychiatric Institute and Clinic, Pittsburgh, PA, 15213

来源：

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1995年 / 10卷 / 03期

关键词：

ISONIAZID; MAOI; TRICYCLIC ANTIDEPRESSANTS; TYRAMINE REACTION;

D O I：

10.1097/00004850-199510030-00009

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Isoniazid is an antitubercular drug with some monamine oxidase (MAO) inhibition. Perhaps because this is only weak inhibition, a few clinicians consider dietary or drug restrictions for their patients on isoniazid. However recent reports suggest the combination of isoniazid and antidepressants may cause adverse events possibly related to isoniazid's MAO inhibition activity. The mechanism of the tyramine reaction and recommendations for cautious combinations of tricyclic antidepressants and isoniazid are discussed.

引用

页码：197 / 198

页数：2

共 14 条

[1]

BIECK PR, 1989, J NEURAL TRANSM-SUPP, V28, P21

[2]

DAPRADA M, 1989, J NEURAL TRANSM-SUPP, V28, P5

[3]

GORKIN VZ, 1983, AMINE OXIDASES CLIN, P1

[4] ISONIAZID AND ANTIDEPRESSANTS - IS THERE CAUSE FOR CONCERN [J].

JUDD, FK ;

MIJCH, AM ;

COCKRAM, A ;

NORMAN, TR .

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 1994, 9 (02) :123-125

[5] ISONIAZID AND REACTION TO CHEESE [J].

LEJONC, JL ;

GUSMINI, D ;

BROCHARD, P .

ANNALS OF INTERNAL MEDICINE, 1979, 91 (05) :793-793

[6]

MAGYAR K, 1993, INHIBITORS MONOAMINE, P133

[7] ISONIAZID AND LEVODOPA [J].

MORGAN, JP .

ANNALS OF INTERNAL MEDICINE, 1980, 92 (03) :434-434

[8]

NELSON JC, 1993, J CLIN PSYCHIAT, V54, P42

[9]

ROBINSON DS, 1986, BIOCHEM PHARMACOL, V17, P109

[10]

SANDLER M, 1979, MONOAMINE OXIDASE ST, P447

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