FATIGUE, SLEEP DISTURBANCES AND CIRCADIAN-RHYTHM IN MULTIPLE-SCLEROSIS

被引：63
|
作者：
TAPHOORN, MJB
VANSOMEREN, E
SNOEK, FJ
STRIJERS, RLM
SWAAB, DF
VISSCHER, F
DEWAAL, IP
POLMAN, CH
机构：
[1] NETHERLANDS INST BRAIN RES,1095 KJ AMSTERDAM,NETHERLANDS
[2] FREE UNIV AMSTERDAM HOSP,DEPT MED PSYCHOL,AMSTERDAM,NETHERLANDS
[3] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,AMSTERDAM,NETHERLANDS
[4] FREE UNIV AMSTERDAM HOSP,DEPT CLIN NEUROPHYSIOL,AMSTERDAM,NETHERLANDS
来源：
JOURNAL OF NEUROLOGY | 1993年 / 240卷 / 07期
关键词：
FATIGUE; SLEEP; CIRCADIAN RHYTHM; MULTIPLE SCLEROSIS;
D O I：
10.1007/BF00867360
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The aim of this study was to investigate whether fatigue and sleep disturbances in multiple sclerosis (MS) patients might be due to disrupted circadian sleep wake regulation. Actigraphy and a multiple sleep latency test (MSLT) were performed in 16 MS patients with both prominent sleep complaints and fatigue. Actigraphy scores did not differ from control values, whereas sleep onset latency values were altered in subgroups of MS patients. No evidence was found for a generalized circadian disturbance in MS patients.
引用
收藏
页码：446 / 448
页数：3
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