INSULIN BOUND TO THE INSULIN-RECEPTOR OF IM-9 LYMPHOCYTES IS MORE ACCESSIBLE TO ANTIINSULIN - ANTIBODIES AFTER TREATMENT WITH DITHIOTHREITOL - BOUND INSULIN IS DEEPLY BURIED IN THE RECEPTOR-BINDING SITE

被引：8

作者：

MCELDUFF, A ^{[1
]}

SCHROER, JA ^{[1
]}

TAYLOR, SI ^{[1
]}

机构：

[1] NIAID, IMMUNOGENET LAB, BETHESDA, MD 20205 USA

来源：

ENDOCRINOLOGY | 1984年 / 115卷 / 05期

关键词：

D O I：

10.1210/endo-115-5-1869

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1869 / 1875

页数：7

共 27 条

[1] AUTOANTIBODIES TO INSULIN RECEPTOR - EFFECT ON INSULIN-RECEPTOR INTERACTION IN IM-9 LYMPHOCYTES
FLIER, JS
KAHN, CR
JARRETT, DB
ROTH, J
JOURNAL OF CLINICAL INVESTIGATION, 1977, 60 (04): : 784 - 794
[2] INSULIN-INDUCED LOSS OF THE INSULIN-RECEPTOR IN IM-9 LYMPHOCYTES - A BIOLOGICAL PROCESS MEDIATED THROUGH THE INSULIN-RECEPTOR
KOSMAKOS, FC
ROTH, J
JOURNAL OF BIOLOGICAL CHEMISTRY, 1980, 255 (20) : 9860 - 9869
[3] GLYCOSYLATION IS ESSENTIAL FOR THE BIOSYNTHETIC PROCESSING OF THE INSULIN-RECEPTOR OF IM-9 LYMPHOCYTES
WHITTAKER, J
ROTH, J
DIABETOLOGIA, 1984, 27 (02) : A345 - A346
[4] GLUCOCORTICOID REGULATION OF INSULIN-RECEPTOR GENE-TRANSCRIPTION IN IM-9 CULTURED LYMPHOCYTES
MCDONALD, AR
GOLDFINE, ID
JOURNAL OF CLINICAL INVESTIGATION, 1988, 81 (02): : 499 - 504
[5] INSULIN RECEPTOR-BINDING AND DEGRADATION IN IM-9 CULTURED HUMAN-LYMPHOCYTES - IMPORTANCE OF EXTRACELLULAR DEGRADATION
MISBIN, RI
MEHL, TD
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1980, 3 (01) : 77 - 81
[6] A PEPTIDE BASED RADIOIMMUNOASSAY FOR INSULIN-RECEPTOR - DETECTION OF INSULIN STIMULATED DOWN REGULATION OF RECEPTOR IN IM-9 CELLS
MCFARLAND, KC
RAMACHANDRAN, J
GRUNFELD, C
FASEB JOURNAL, 1988, 2 (06): : A1796 - A1796
[7] PEPTIDE-BASED RADIOIMMUNOASSAY FOR INSULIN-RECEPTOR - DETECTION OF INSULIN-STIMULATED DOWN-REGULATION IN IM-9 LYMPHOCYTES
MCFARLAND, KC
RAMACHANDRAN, J
GRUNFELD, C
DIABETES, 1989, 38 (08) : 987 - 990
[8] INSULIN-MEDIATED INSULIN-RECEPTOR DOWN REGULATION IN IM-9 LYMPHOCYTES - PARALLEL STUDIES IN WHOLE CELLS AND SOLUBILIZED RECEPTORS
WHITSON, RH
KAPLAN, SA
FEDERATION PROCEEDINGS, 1982, 41 (04) : 1341 - 1341
[9] First view of insulin bound to its primary binding site on the insulin receptor
Lawrence, Michael
Menting, John
Kong, Geoffrey
Margetts, Mai
Ward, Colin
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2011, 67 : C146 - C146
[10] STRUCTURE OF THE INSULIN-RECEPTOR OF THE CULTURED HUMAN-LYMPHOBLASTOID CELL IM-9 - EVIDENCE SUGGESTING THAT 2 SUBUNITS ARE REQUIRED FOR INSULIN BINDING
POLLET, RJ
KEMPNER, ES
STANDAERT, ML
HAASE, BA
JOURNAL OF BIOLOGICAL CHEMISTRY, 1982, 257 (02) : 894 - 898

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