Aging and Circadian Rhythms

被引:217
作者
Duffy, Jeanne F. [1 ,2 ,3 ]
Zitting, Kirsi-Marja [1 ,2 ,3 ]
Chinoy, Evan D. [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Dept Med, Div Sleep & Circadian Disorders, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Neurol, Div Sleep & Circadian Disorders, Boston, MA 02115 USA
[3] Harvard Med Sch, Div Sleep Med, Boston, MA USA
关键词
Aging; Circadian; Human; Light; Melatonin; Sleep;
D O I
10.1016/j.jsmc.2015.08.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Aging is associated with numerous changes, including changes in sleep timing, duration, and quality. The circadian timing system interacts with a sleep-wake homeostatic system to regulate human sleep, including sleep timing and structure. This article reviews key features of the human circadian timing system, age-related changes in the circadian timing system, and how those changes may contribute to the observed alterations in sleep. © 2015 Elsevier Inc.
引用
收藏
页码:423 / 434
页数:12
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