Aging and Circadian Rhythms

被引:235
作者
Duffy, Jeanne F. [1 ,2 ,3 ]
Zitting, Kirsi-Marja [1 ,2 ,3 ]
Chinoy, Evan D. [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Dept Med, Div Sleep & Circadian Disorders, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Neurol, Div Sleep & Circadian Disorders, Boston, MA 02115 USA
[3] Harvard Med Sch, Div Sleep Med, Boston, MA USA
关键词
Aging; Circadian; Human; Light; Melatonin; Sleep;
D O I
10.1016/j.jsmc.2015.08.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Aging is associated with numerous changes, including changes in sleep timing, duration, and quality. The circadian timing system interacts with a sleep-wake homeostatic system to regulate human sleep, including sleep timing and structure. This article reviews key features of the human circadian timing system, age-related changes in the circadian timing system, and how those changes may contribute to the observed alterations in sleep. © 2015 Elsevier Inc.
引用
收藏
页码:423 / 434
页数:12
相关论文
共 178 条
[1]  
Ancoli-Israel Sonia, 2003, Behav Sleep Med, V1, P22, DOI 10.1207/S15402010BSM0101_4
[2]  
AncoliIsrael S, 1997, SLEEP, V20, P18
[3]   SLEEP FRAGMENTATION IN PATIENTS FROM A NURSING-HOME [J].
ANCOLIISRAEL, S ;
PARKER, L ;
SINAEE, R ;
FELL, RL ;
KRIPKE, DF .
JOURNALS OF GERONTOLOGY, 1989, 44 (01) :M18-M21
[4]  
[Anonymous], 2003, EXECUTIVESUMMARY 200
[5]   Age-related effects on the biological clock and its behavioral output in a primate [J].
Aujard, F ;
Cayetanot, F ;
Bentivoglio, M ;
Perret, M .
CHRONOBIOLOGY INTERNATIONAL, 2006, 23 (1-2) :451-460
[6]  
Barker FM, 1991, ARVO ANN M ABSTR
[7]   Responsiveness of the aging circadian clock to light [J].
Benloucif, S. ;
Green, K. ;
L'Hermite-Baleriaux, M. ;
Weintraub, S. ;
Wolfe, L. F. ;
Zee, P. C. .
NEUROBIOLOGY OF AGING, 2006, 27 (12) :1870-1879
[8]   NOCTURNAL SLEEP AND WAKEFULNESS - EFFECTS OF AGE AND SEX IN NORMAL SLEEPERS [J].
BIXLER, EO ;
KALES, A ;
JACOBY, JA ;
SOLDATOS, CR ;
VELABUENO, A .
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 1984, 23 (01) :33-42
[9]   SLEEP IN NORMAL AGING AND DEMENTIA [J].
BLIWISE, DL .
SLEEP, 1993, 16 (01) :40-81
[10]   SLEEP IN NORMAL AND PATHOLOGICAL AGING [J].
BLOIS, R ;
FEINBERG, I ;
GAILLARD, JM ;
KUPFER, DJ ;
WEBB, WB .
EXPERIENTIA, 1983, 39 (06) :551-558