The Effects of NF-kappa B Inhibitors on Bone Formation

被引：1
|
作者：
Aoki, Kazuhiro [1 ]
机构：
[1] Tokyo Med & Dent Univ, Grad Sch, Dept Hard Tissue Engn Pharmacol, Bunkyo Ku, 1-5-45 Yushima, Tokyo 1138549, Japan
来源：
JOURNAL OF ORAL BIOSCIENCES | 2010年 / 52卷 / 04期
关键词：
bone formation; NF-kappa B; anabolic reagent;
D O I：
10.2330/joralbiosci.52.303
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The transcription factor nuclear factor-kappa B ( NF-kappa B) plays a pivotal role in the regulation of the immune system, including the inflammatory response. The NF-kappa B signaling pathways also play an important role in bone homeostasis, especially in regard to osteoclast differentiation. The role of NF-kappa B in bone formation, however, remains to be fully elucidated. In this review, the effects of NF-kappa B inhibitors, focusing on bone formation, are described based on our findings.
引用
收藏
页码：303 / 310
页数：8
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