VARIATIONS AND CODING FEATURES OF THE SEQUENCE SPANNING THE REPLICATION TERMINUS OF BACILLUS-SUBTILIS 168 AND W23-CHROMOSOMES

被引:23
作者
AHN, KS [1 ]
WAKE, RG [1 ]
机构
[1] UNIV SYDNEY,DEPT BIOCHEM,SYDNEY,NSW 2006,AUSTRALIA
基金
澳大利亚研究理事会;
关键词
CYTOCHROME P-450; RECOMBINANT DNA; OXIDOREDUCTASE SUPERFAMILY; PROC; TERC;
D O I
10.1016/0378-1119(91)90111-N
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
In a comparative study of the sequences of the 3-kb regions of DNA spanning the replication terminus, terC, of Bacillus subtilis strains 168 and W23, it was found that the latter contained an insertion of a large open reading frame (ORF405) whose translated protein product is a member of the cytochrome P-450 family. The insertion was about 34 nucleotides upstream from a putative promoter for the rtp gene. The sequenced regions contained a number of other ORFs. The translation product of one (ORF238) is a member of a previously identified oxidoreductase superfamily. The translation product of another (ORF257) is significantly similar to the proC product of Escherichia coli, but this ORF does not code for a functional proC product of B. subtilis.
引用
收藏
页码:107 / 112
页数:6
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