ISOLATION AND IDENTIFICATION OF ANTIMICROBIAL COMPOUNDS IN BRAZILIAN PROPOLIS

被引：183

作者：

AGA, H ^{[1
]}

SHIBUYA, T ^{[1
]}

SUGIMOTO, T ^{[1
]}

KURIMOTO, M ^{[1
]}

NAKAJIMA, S ^{[1
]}

机构：

[1] OKAYAMA UNIV, FAC AGR, DEPT BIORESOURCES CHEM, OKAYAMA 700, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1994年 / 58卷 / 05期

关键词：

D O I：

10.1271/bbb.58.945

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three distinct antimicrobial compounds were isolated from Brazilian propolis. These compounds sere identified as 3,5-diprenyl-4-hydroxycinnamic acid (1), 3-prenyl-4-dihydrocinnamoloxycinnamic acid (2), and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzo (3). The respective antimicrobial activity, expressed as MIC is mu g/ml, 1-3 against Bacillus cereus was 15.6, 31.3, and 125; that against Enterobacter aerogenes was 31.3, 62.5, and 125; and that against Arthroderma benhamiae was 15.6, >250, and 62.5. Compound 1 is likely to be one of the major antimicrobial compounds in Brazilian propolis.

引用

页码：945 / 946

页数：2

共 11 条

[1]

AGA H, 1992, MED BIOL, V124, P205

[2] NEW SESQUITERPENE ACIDS, SESQUITERPENE DIOL, FLAVANONES AND OTHER AROMATIC-COMPOUNDS FROM FLOURENSIA-HETEROLEPIS .198. NATURALLY OCCURRING TERPENE DERIVATIVES [J].

BOHLMANN, F ;

JAKUPOVIC, J .

PHYTOCHEMISTRY, 1979, 18 (07) :1189-1194

[3]

FUJIMURA H, 1985, Patent No. 85163841

[4] PROPOLIS - REVIEW [J].

GHISALBERTI, EL .

BEE WORLD, 1979, 60 (02) :59-84

[5]

KAWAI S, 1993, MED BIOL, V126, P183

[6]

KOUDA M, 1993, Patent No. 9358943

[7] SECONDARY METABOLITES FROM CHILEAN BACCHARIS SPECIES [J].

LABBE, C ;

ROVIROSA, J ;

FAINI, F ;

MAHU, M ;

SANMARTIN, A ;

CASTILLO, M .

JOURNAL OF NATURAL PRODUCTS, 1986, 49 (03) :517-518

[8]

METZNER J, 1979, PHARMAZIE, V34, P97

[9]

MITSUHASHI S, 1981, CHEMOTHERAPY, V29, P76

[10]

Tatefuji Tomoki, 1993, Shoyakugaku Zasshi, V47, P60

← 1 2 →