RELATIONSHIP BETWEEN THE MIC LEVELS OF 5 ANTISEPTICS AND PRESENCE OF THE QACA GENE IN STAPHYLOCOCCUS-AUREUS

被引：0

作者：

BEHR, H ^{[1
]}

REVERDY, ME ^{[1
]}

MABILAT, C ^{[1
]}

FRENEY, J ^{[1
]}

FLEURETTE, J ^{[1
]}

机构：

[1] ENS LYON,F-69364 LYON 07,FRANCE

来源：

PATHOLOGIE BIOLOGIE | 1994年 / 42卷 / 05期

关键词：

STAPHYLOCOCCUS-AUREUS; ANTISEPTICS; QACA GENE; PCR;

D O I：

暂无

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The Polymerase Chain Reaction (PCR) was used to detect the qacA gene which encodes antiseptic resistance in 186 clinical isolates of Staphylococcus aureus. The results were compared with those obtained by MIC determination of 4 antiseptics benzalkonium chloride, hexamidine, chlorhexidine, (acriflavine) and for ethidium bromide. The qacA gene was not detected among the 32 susceptible S. aureus strains, but was found in the 70 (85%) of the 82 S. aureus strains resistant to all 5 antiseptics. The gene was also detected in 70 (45%) of the 154 remaining strains that were resistant to at least one antiseptic.

引用

页码：438 / 444

页数：7

共 11 条

[1]

GILLESPIE MT, 1988, J GEN MICROBIOL, V134, P2857

[2] DETECTION OF GYRA GENE-MUTATIONS ASSOCIATED WITH CIPROFLOXACIN RESISTANCE IN METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS - ANALYSIS BY POLYMERASE CHAIN-REACTION AND AUTOMATED DIRECT DNA SEQUENCING [J].