Future of cardiac resynchronization therapy

被引:0
作者
Arujuna, Aruna Vishnu [1 ]
Ginks, Matthew [1 ]
Rinaldi, Aldo [1 ]
机构
[1] St Thomas Hosp, London SE1 7EH, England
关键词
cardiac resynchronization therapy; dyssynchrony; heart failure;
D O I
10.2217/14796678.4.2.191
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac resynchronization therapy (CRT) has proven to be a beneficial treatment option in patients with severe drug refractory heart failure in the presence of electromechanical dyssynchrony. More recent trials have demonstrated mortality benefits associated with CRT, and even further reductions when combined with an internal cardiac defibrillator. Addressing the 20-30% cohort of patients who do not derive benefit from this novel therapy is a rapidly emerging area of research activity with encouraging results. Here we review the CRT trial evidence that forms the basis of patient-selection guidelines for device implantation and describe the present outstanding issues, alongside identifying future trends in CRT that appear promising.
引用
收藏
页码:191 / 201
页数:11
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